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Prolific Machines

Research Associate, Applied Cell Line Development & Customer Programs

Emeryville, California · Full-time

$73K–$118K

Series B · $50M · 26d ago Posted 2d ago
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Why join Prolific Machines?

As drugmakers chase harder molecules like bispecifics, manufacturing yield is becoming the bottleneck. Prolific Machines, a biotechnology company in Emeryville, California, is betting that light can steer protein production, and if it works, drug developers and CDMOs could build on it. A $50M Series B from Mayfield, SOSV and Breakthrough Energy Ventures is bigger than 46% of its stage peers, and five of seven open roles went live this past month.

JustBacked's take, based on Prolific Machines's own site and its funding and hiring data.

Prolific Machines is ushering in a new era of biotechnology with light. Our first-of-its-kind optogenetic platform delivers unprecedented control, precisely guiding cellular behavior when and where it matters most. Unlike existing tools used to control biology, our technology enables dynamic, tunable control over virtually any cellular function in any cell type. We're enabling partners to unlock robust efficiency, quality, and reproducibility advantages across the most complex pharmaceuticals and therapeutic proteins. Prolific is supported by leading investors, including Bill Gates’s Breakthrough Energy Ventures, Mayfield and SOSV.


We are looking for a motivated and detail-oriented Research Associate to help advance our mammalian cell line development and protein production capabilities. At Prolific, we use light to control the expression of biotherapeutic proteins, with the goal of increasing titer and improving quality attributes. In this role, you will play a key part in generating and characterizing cell lines that support both internal research and customer programs. The ideal candidate enjoys hands-on laboratory work, takes pride in delivering consistent, high-quality results, and is eager to learn and grow in a fast-paced startup environment. You’ll collaborate with scientists and engineers across multiple disciplines, with opportunities to expand your technical expertise, take on increasing ownership, and contribute directly to Prolific’s success. This role is based on-site in our headquarters in Emeryville, CA.

Benefits: Generous equity package in an early stage company, retirement plan with company contribution, flexible PTO with healthy time off minimums, company-covered medical, dental, and vision insurance, life and disability insurance, career coaching, mental health support, free team lunches everyday, great snacks, and companywide social events!

Diversity: Prolific Machines values diverse perspectives, backgrounds, experiences, and ideas. We are committed to building an inclusive workplace where all employees can bring their authentic selves to work and have equal opportunities to succeed. Prolific Machines is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, religion, creed, sex, gender identity or expression, sexual orientation, national origin, ancestry, age, disability, medical condition, genetic information, marital status, military or veteran status, or any other characteristic protected by applicable law.

Location: The San Francisco Bay Area (Emeryville, CA)